Learn about the potential side effects of Nexium (esomeprazole). Includes common and rare side effects information for consumers and healthcare professionals. Learn about Nexium (Esomeprazole Magnesium) may treat, uses, dosage, side effects, drug interactions, warnings, patient labeling, reviews, and related medications. Nexium and the other proton-pump inhibitors are great at reducing stomach acid, but that might have some unintended consequences. Madison Avenue has given stomach acid a bad name, but it's really kind of a bum rap. A 2006 study published in the Journal of the American Medical Association shows that long-term use of Nexium and other proton pump inhibitors increases the risk of hip fractures in people over 50. Nexium benefit and side effects, risk, danger, safety esomeprazole December 12 2017 by Ray Sahelian, M.D. Nexium is in a class of drugs called proton pump inhibitors (PPIs) which block the production of acid by the stomach. Nexium (esomeprazole magnesium) is a proton pump inhibitor (PPI) that blocks acid production in the stomach and is used to treat stomach and duodenal ulcers, gastroesophageal reflux disease , and Zollinger-Ellison syndrome. Nexium is used to treat GERD and other conditions involving excessive stomach acid. Learn about side effects, interactions and indications. Information on the drug esomeprazole (Nexium, Nexium 24HR, Nexium IV) an over-the-counter and prescription drug used to treat gastroesophageal reflux disease (GERD), in combination with antibiotics to treat H. pylori infection, Zollinger-Ellison syndrome treatment, and reducing the risk of gastric ulcers. Side effects, drug interactions, and. Nexium is a proton pump inhibitor (PPI) intended to reduce the amount of acid in a person’s stomach. Learn about the most common uses & side effects. Nexium, or esomeprazole, is a proton pump inhibitor. It is used to treat gastroesophageal reflux disease, duodenal ulcer disease, and erosive esophagitis.